Where can I find the primary clinical evidence?

Primary trials are published in peer-reviewed journals (NEJM, JAMA, Lancet) with PubMed PMIDs cited throughout US Telehealth Review.

Side Effects — Detailed Profile | US Telehealth Review

Side Effects

Most common: nausea (44%), diarrhea (30%), vomiting (24%), constipation (24%). Mostly mild-moderate and titration-dependent. Serious AEs <1% in published cohorts.

Clinical referencePubMed-linkedUpdated 2026-05-08

Editorial team

Dr. Sam Saberian · Lead Medical Researcher

Medical review by Alen A. Schwartz, MD · Edited by Julliana Edwards · Last updated 2026-05-11

Overview

Most common: nausea (44%), diarrhea (30%), vomiting (24%), constipation (24%). Mostly mild-moderate and titration-dependent. Serious AEs <1% in published cohorts.

PubMed citations

PMID 33567185

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STEP trial results
SELECT trial results
FLOW trial results
Mechanism of action
Dosing & pharmacology
Contraindications
Side effects