Where can I find the primary clinical evidence?

Primary trials are published in peer-reviewed journals (NEJM, JAMA, Lancet) with PubMed PMIDs cited throughout US Telehealth Review.

Contraindications & Boxed Warning | US Telehealth Review

Contraindications & Boxed Warning

Semaglutide is contraindicated in MTC, MEN 2, pregnancy, breastfeeding. Boxed warning: thyroid C-cell tumors (rodent studies, human relevance unknown).

Clinical referenceUpdated 2026-05-08

Editorial team

Dr. Sam Saberian · Lead Medical Researcher

Medical review by Alen A. Schwartz, MD · Edited by Julliana Edwards · Last updated 2026-05-11

Overview

Semaglutide is contraindicated in MTC, MEN 2, pregnancy, breastfeeding. Boxed warning: thyroid C-cell tumors (rodent studies, human relevance unknown).

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SELECT trial results
FLOW trial results
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Dosing & pharmacology
Contraindications
Side effects