Growth Hormone · GHRP

GHRP-6

GHRP-6 is a synthetic growth hormone-releasing peptide with significant appetite-stimulating effects due to its potent ghrelin-receptor activation. Used to increase GH and food intake.

Category: Growth Hormone Secretagogues Last updated 2026-05-11
GHRP-6 at a glance

GHRP-6 is a synthetic growth hormone-releasing peptide with significant appetite-stimulating effects due to its potent ghrelin-receptor activation. Used to increase GH and food intake. Mechanism: GHRP / GH secretagogue. Typical route: Subcutaneous. FDA status: Not FDA-approved. Dispensed by compounding pharmacies; less commonly used in modern protocols than Ipamorelin given the appetite effect.

Drug classGHRP / GH secretagogue
Half-life~30 minutes
RouteSubcutaneous
Common dosing100-200 mcg, 2-3x/day
FDA statusNot approved
Available throughCompounding pharmacies

Mechanism of action

GHRP-6 binds the ghrelin receptor (GHS-R1a) and stimulates pituitary GH release. Compared with GHRP-2, GHRP-6 has a stronger appetite-stimulating effect, which can be desirable for patients trying to gain weight but undesirable for body-composition goals.

Dosing reference

Subcutaneous: 100-200 mcg, two to three times daily. Often combined with CJC-1295 or modified GRF (1-29) for stronger and more sustained GH pulses.

Dosing information is provided for educational reference and is not medical advice. Patients should not initiate or modify any peptide regimen without consulting a licensed clinician. See our medical disclaimer.

FDA status & regulatory framework

Not FDA-approved. Dispensed by compounding pharmacies; less commonly used in modern protocols than Ipamorelin given the appetite effect.

U.S. telehealth providers that work with GHRP-6

#1 of 4
88/100v3.0 six-pillar rubric

Starting at $160/mo. Defy Medical is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-6.

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#2 of 4
85/100v3.0 six-pillar rubric

Starting at $180/mo. Marek Health is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-6.

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#3 of 4
76/100v3.0 six-pillar rubric

Starting at $149/mo. Maximus is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-6.

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#4 of 4
80/100v3.0 six-pillar rubric

Starting at $149/mo. Hone Health is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-6.

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Frequently asked questions about GHRP-6

Does GHRP-6 cause hunger?

Yes. GHRP-6 has the strongest appetite-stimulating effect of the common GHRPs. This makes it useful for patients with poor appetite but unsuitable for weight-management goals.

What is the difference between GHRP-6 and Ipamorelin?

Ipamorelin is a 'cleaner' GH stimulator with minimal appetite, prolactin, or cortisol effects. Most modern protocols favor Ipamorelin (often combined with CJC-1295) over GHRP-6.

Lead Medical Researcher
Dr. Sam Saberian
Doctor of Pharmacy; leads protocol research, peptide pharmacology, and provider evaluation.
Medical Reviewer
Alen A. Schwartz, MD
Board-certified physician; reviews clinical accuracy of every published page.
Edited by
Julliana Edwards
Editorial standards, factual accuracy, and corrections workflow.