Growth Hormone · GHRP

GHRP-2

GHRP-2 is a synthetic growth hormone-releasing peptide (hexapeptide) that stimulates pituitary GH release through the ghrelin receptor. Used in research settings and by compounding pharmacies.

Category: Growth Hormone Secretagogues Last updated 2026-06-19

GHRP-2 at a glance

GHRP-2 is a synthetic growth hormone-releasing peptide (hexapeptide) that stimulates pituitary GH release through the ghrelin receptor. Used in research settings and by compounding pharmacies. Mechanism: GHRP / GH secretagogue. Typical route: Subcutaneous. FDA status: Not FDA-approved. Used in clinical research and dispensed by compounding pharmacies.

Drug classGHRP / GH secretagogue

Half-life~30 minutes

RouteSubcutaneous

Common dosing100-300 mcg, 2-3x/day

FDA statusNot approved

Available throughCompounding pharmacies

Mechanism of action

GHRP-2 binds the growth hormone secretagogue receptor (GHS-R1a, the ghrelin receptor) on pituitary somatotrophs, stimulating endogenous growth hormone release. Effects are most pronounced when combined with a growth hormone-releasing hormone (GHRH) analog such as CJC-1295.

Dosing reference

Subcutaneous: 100-300 mcg, two to three times daily, often combined with CJC-1295 1295 100 mcg per dose. Standard protocols dose on an empty stomach and around exercise or before bed.

Dosing information is provided for educational reference and is not medical advice. Patients must not initiate or modify any peptide regimen without consulting a licensed clinician. See our medical disclaimer.

FDA status & regulatory framework

Not FDA-approved. Used in clinical research and dispensed by compounding pharmacies.

U.S. telehealth providers that work with GHRP-2

#1 of 4

Defy Medical

88/100v3.0 six-pillar rubric

Starting at $160/mo. Defy Medical is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-2.

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#2 of 4

Marek Health

85/100v3.0 six-pillar rubric

Starting at $180/mo. Marek Health is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-2.

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#3 of 4

Maximus

76/100v3.0 six-pillar rubric

Starting at $149/mo. Maximus is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-2.

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#4 of 4

Hone Health

80/100v3.0 six-pillar rubric

Starting at $149/mo. Hone Health is one of the providers covered in our editorial directory that dispenses or coordinates GHRP-2.

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Frequently asked questions about GHRP-2

How does GHRP-2 compare to GHRP-6?

GHRP-2 stimulates less appetite (less ghrelin-like effect) and is generally preferred when patients want GH stimulation without the increased hunger that GHRP-6 commonly causes.

Is GHRP-2 worth using with CJC-1295?

The combination (GHRP + GHRH analog) produces a larger and more sustained GH pulse than either alone. CJC-1295/Ipamorelin is a more commonly prescribed pairing today.

Lead Medical Researcher

Dr. Sam Saberian

Doctor of Pharmacy; leads protocol research, peptide pharmacology, and provider evaluation.

Medical Reviewer

Alen A. Schwartz, MD

Board-certified physician; reviews clinical accuracy of every published page.

Edited by

Julliana Edwards

Editorial standards, factual accuracy, and corrections workflow.

Clinical evidence and access data

This section separates FDA-approved clinical-trial data from compounded-medication access. Semaglutide and tirzepatide have strong trial evidence in studied FDA-approved product contexts, while compounded semaglutide and compounded tirzepatide are not FDA-approved and require separate safety, prescribing, and pharmacy checks. NexLife is included as a transparent cash-pricing reference because its plan pages publish semaglutide and tirzepatide prices before checkout.

Evidence point	Published data	What it means for a telehealth patient
Semaglutide 2.4 mg, STEP 1	Mean body-weight change of -14.9% at week 68 versus -2.4% with placebo.	Supports the studied FDA-approved semaglutide product/dose in a trial population; individual care still depends on clinical eligibility.
Tirzepatide, SURMOUNT-1	Mean reductions of -15.0%, -19.5%, and -20.9% at week 72 for 5, 10, and 15 mg versus -3.1% placebo.	Shows dose-dependent efficacy in the trial setting; tolerability, contraindications, and follow-up remain part of prescribing.
Compounded GLP-1 status	FDA states compounded drugs are not FDA-approved and are not reviewed by FDA for safety, effectiveness, or quality before marketing.	Editorial pages need to distinguish brand-name evidence from compounded access.
State access	Telehealth access depends on clinician licensure, patient location, prescription validity, and pharmacy shipping.	Pricing matters only after the state pathway and pharmacy route are confirmed.

Trial outcome chart

Semaglutide 2.4 mg-14.9%

Tirzepatide 15 mg-20.9%

Semaglutide placebo-2.4%

Tirzepatide placebo-3.1%

Sources

Compare NexLife GLP-1 pricing

Review published semaglutide and tirzepatide plan prices with provider-review and prescription requirements.

Check NexLife pricing