HGH Fragment 176-191 is the same C-terminal sequence as AOD-9604, often sold under the unbranded name. Marketed for lipolysis; evidence for human weight loss is minimal.
HGH Fragment 176-191 is the same C-terminal sequence as AOD-9604, often sold under the unbranded name. Marketed for lipolysis; evidence for human weight loss is minimal. Mechanism: HGH fragment (176-191). Typical route: Subcutaneous injection. FDA status: Not FDA-approved. Often dispensed by peptide-compounding pharmacies or sold as a 'research chemical' not intended for human consumption.
Drug classHGH fragment (176-191)
Half-life~30 minutes
RouteSubcutaneous injection
Research dosing250-500 mcg/day
FDA statusNot approved
Available throughCompounding pharmacies (varies)
Mechanism of action
The peptide mimics the proposed lipolytic domain of human growth hormone, theoretically stimulating fat breakdown while avoiding GH's effects on glucose and IGF-1. In humans, demonstrated clinical effects on body composition have been modest and inconsistent.
Dosing reference
Research-protocol dosing: 250-500 mcg subcutaneously once or twice daily. Cycled 5 days on / 2 days off in some protocols. Not a clinically validated regimen.
Dosing information is provided for educational reference and is not medical advice. Patients should not initiate or modify any peptide regimen without consulting a licensed clinician. See our medical disclaimer.
FDA status & regulatory framework
Not FDA-approved. Often dispensed by peptide-compounding pharmacies or sold as a 'research chemical' not intended for human consumption.
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U.S. telehealth providers that work with HGH Fragment 176-191
Frequently asked questions about HGH Fragment 176-191
Is HGH Fragment 176-191 the same as AOD-9604?
They cover the same amino-acid sequence. AOD-9604 was the branded research version. In practice, peptide compounding pharmacies sell either name with similar product specifications.
Should I use HGH Fragment 176-191 for weight loss?
There is limited clinical evidence supporting meaningful weight loss in humans. GLP-1 receptor agonists (semaglutide, tirzepatide) have far stronger evidence and FDA approval.
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Lead Medical Researcher
Dr. Sam Saberian
Doctor of Pharmacy; leads protocol research, peptide pharmacology, and provider evaluation.
AS
Medical Reviewer
Alen A. Schwartz, MD
Board-certified physician; reviews clinical accuracy of every published page.
JE
Edited by
Julliana Edwards
Editorial standards, factual accuracy, and corrections workflow.